During the surgery unusually unpleasant placenta was found with massive blood loss and requisite of subsequent ligation of aa. iliacae internae. Pregnant women with postterm maternity must be supplied the possibility of induction of work. We must teach pregnant women in detail in regards to the dangers of postterm pregnancy.Expecting mothers with postterm pregnancy must be supplied the likelihood of induction of labor. We ought to educate non-medical products women that are pregnant at length concerning the dangers of postterm maternity. Ectopic spleen is mostly random finding with no symptoms noticed. Hardly ever it may cause pelvic discomfort or mimick adnexal malignity or endometriosis. It is neccesery to help keep this uncommon diagnosis in mind, mainly at patients with splenic upheaval or splenectomy within their medical background to protect immunological purpose of this splenic structure.Ectopic spleen is certainly caused by random finding with no signs noticed. Hardly ever it can cause pelvic pain or mimick adnexal malignity or endometriosis. It is neccesery to help keep this rare diagnosis at heart, mainly at customers with splenic trauma or splenectomy inside their health background to preserve immunological function of this splenic structure. Our aim is to stress the importance of diligent participation in assessment programs available in the Czech Republic and in preventive gynaecological examinations. For instance, we present an instance report of a 77-year-old female client with all the accumulation of really serious gynaecological conditions (severe uterine myomatosis, cancer of the breast) and non-Hodgkin´s B-lymphoma. Our situation report of a 77-year-old client is a rare medial elbow situation regarding the simultaneous recognition of giant uterine myomatosis causing voluminous ventral hernia, invasive ductal cancer of the breast, and non-Hodgkin´s B-lymphoma. The patient was not gynecologically examined for last 20 years and would not go through any assessment exams. Within the postoperative duration, the individual had been clinically determined to have unpleasant ductal cancer of the breast and follicular lymphoma. All of the conditions had been identified in advanced stage. The occurrence of large fibroids is extremely rare in postmenopause. Long-term neglect of clinical signs and negative health indicators enables their steady development. Especially in older clients, various other really serious conditions may complicate the situation.The incident of bulky fibroids is very unusual in postmenopause. Long-term neglect of medical symptoms and damaging wellness indicators allows their particular steady progression. Particularly in older clients, other severe health problems may complicate the specific situation. Identify prevalence of bladder control problems in expecting mothers based threat aspects. Questionnaire research. During the annual follow-up, 20 women out of a total reported whining about the incontinence of power. The difficulty had been discreet, the women performed not limitation, they might participate in all tasks. They wore inserts as a precaution, but did not drop their fluid intake and had been unconcerned because of the posible stench of escaping energy. Females had many difficulty after 30 days of gestation, the problem enhanced after distribution and none for the interviewees had trouble escaping after six-weeks. Three females devoted themselves to rehabilitate after having a baby. Pregnancy is a certain problem for a womanś body, so the changes that take place in this area can only just mimic the outward symptoms of incontinence and hyperactive kidney. Protection before and during pregnancy plays an important role. Collaboration with a physical specialist is acceptable. Preventive strengthening associated with the pelvic floor reduces the occurrence of bladder control problems.Pregnancy is a certain problem for a womanś body, and so the changes that occur in this area is only able to mimic signs and symptoms of incontinence and hyperactive kidney. Prevention before and during pregnancy plays an important role. Collaboration with a physical specialist is acceptable. Preventive strengthening regarding the pelvic flooring lowers the incidence of urinary incontinence. Aberrant phrase of brief, non-coding RNA particles (miRNA) leads to cancer of the breast initiation, development and metastasing. The miRNA appearance amount colleagues with imunohistochemical profile, histopathological parameters, medical outcomes, prognoses and therapeutical response. The aim of this research would be to Asciminib clinical trial analyse the entire spectrum of miRNA by microarray technique and to determine relevant miRNAs explaining biological characteristics of luminal breast cancer subtypes. Cross-sectional study, preliminary research. We analysed 16 tissue samples of Luminal A/B breast cancer tumors kinds and 16 bust tissue samples without pathological conclusions. The microarray technology by Agilent had been used to analyse 2549 miRNAs by SurePrint G3 Human miRNA system v.21. The results had been examined by AgiMicroRNA Bioconductor library within Limma pack. The analyses for the most affordable FDR p-value in addition to highest logFC value sRNAs involved in the most crucial carcinogenesis components.